Pengaruh Tawa Terhadap Kadar Glukosa Darah

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Tertawalah sebelum tertawa itu dilarang!


Mungkin kita sering mendengar kalimat seperti di atas. Tawa merupakan sebuah anugerah yang diberikan Tuhan pada kita. Tawa adalah salah satu ekspresi yang membuat kita 'hidup'. Bayangkan jika dalam sehari anda tidak bisa melakukan ekspresi satu pun seperti senyum, marah atau tertawa. Rasanya seperti orang yang patah hati karena ditinggal kawin.

Oke, fokus... Tawa ternyata memiliki pengaruh yang lebih jauh lagi terhadap tubuh kita. Sudah banyak penelitian yang mengungkapkan bagaimana tawa bersama dengan kebahagiaan dan berpikir positif dapat mempengaruhi tubuh kita. 

Beberapa waktu lalu saya menemukan sebuah jurnal penelitian ketika sedang iseng nyari contoh jurnal Analis Kesehatan. *persiapan bro* Dalam jurnal penelitian tersebut dijelaskan tentang pengaruh tawa. Berikut penuturan Prof. Kazuo Murakami yang saya kutip dari bukunya yang inspiratif berjudul "Tuhan Dalam Gen Kita"

Secara spesifik kami memfokuskan pada bagaimana tawa dapat mempengaruhi tingkat glukosa darah pada orang-orang yang mengidap diabetes tipe 2. Dalam penelitian ini kami mengukur kadar glukosa darah setelah berpuasa (fasting blood glucose atau FGB) para subjek tes. Setelah itu, sebagian dari mereka mendengarkan kuliah yang tidak lucu sementara yang lain menonton sebuah acara komedi. Kemudian, makanan pun dihidangkan bagi mereka, dan setelah itu kami mengukur glukosa darah setelah makan (post prandial blood glucose atau PPBG) mereka.

Dalam percobaan pertama, mereka yang mengikuti kuliah mengalami peningkatan glukosa darah sebesar 123 mg/dl, sementara mereka yang menonton acara komedi hanya mengalami peningkatan sebesar 77 mg/dl. Kami mengulang percobaan tersebut dan sekali lagi, mereka yang menyaksikan acara komedi mengalami peningkatan PPBG yang jauh lebih kecil daripada mereka yang tidak menyaksikannya.

Penelitian tersebut menunjukkan bahwa tawa memiliki efek yang menguntungkan bagi tingkat glukosa darah. Kami menemukan bahwa dua puluh tiga gen teraktivasi berkat tawa


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Berikut Jurnal lengkapnya...

Laughter Lowered the Increase in Postprandial Blood Glucose

Negative emotions such as anxiety, fear, and sorrow are known to be factors that elevate the blood glucose level (1). Conversely, positive emotions such as laughter have been reported to modify the levels of neuroendocrine factors involved in negative emotions (2,3) and to modulate immune function (3,4). However, there have been no studies on the effects of laughter on blood glucose level. The purpose of this study was to clarify changes in the blood glucose level after laughing episodes in patients with diabetes.
A 2-day experiment was performed in 19 patients with type 2 diabetes not receiving insulin therapy (16 men and 3 women, age 63.4 ± 1.3 years, BMI 23.5 ± 0.7 kg/m2, HbA1c, 7.2 ± 0.1% [means ± SE]) and 5 healthy subjects (2 men and 3 women, age 53.6 ± 3.5 years, BMI 24.3 ± 1.6 kg/m2, HbA1c 4.8 ± 0.1% [means ± SE]). On both experimental days, they consumed the same 500-kcal meal (79.9 g carbohydrate, 21.0 g protein, 7.8 g fat, and 1.0 g fiber). On the first day, they attended a monotonous lecture (40 min) without humorous content. On the second day, as part of an audience of 1,000 people attending MANZAI (a Japanese cross-talk comedy) (40 min) in a civic hall, the subjects laughed. Blood glucose was measured from the fingertip by enzyme colorimetric assay using a blood glucose self-measurement apparatus. The subjects estimated their laughter level on a scale of 0–5, and most of them considered that they laughed well (level 4 or 5). Self-monitoring of blood glucose was performed before food intake (fasting blood glucose [FBG]) and 2 h after the meal was started (2-h postprandial blood glucose [PPBG]).
The results are presented as means ± SE. In the patients, the mean 2-h PPBG was 6.8 ± 0.7 mmol/l higher than the FBG after the lecture and 4.3 ± 0.8 mmol/l higher after the comedy show. The difference in the mean increase between the lecture and comedy show was 2.5 ± 0.7 mmol/l (P < 0.005). In the healthy subjects, the mean increases were 2.0 ± 0.7 and 1.2 ± 0.4 mmol/l after the lecture and comedy show, respectively, and the difference was 0.8 ± 0.5 mmol/l (P = 0.138).
These results suggest a significant suppression of the increase in 2-h PPBG by comedy show in patients with diabetes, suggesting that laughter ameliorates the postprandial glucose excursion in the presence of insufficient insulin action. This favorable effect of laughter may include the acceleration of glucose utilization by the muscle motion during the comedy show. However, it is possible that positive emotions such as laughter acted on the neuroendocrine system and suppressed the elevation of blood glucose level.
In conclusion, the present study elucidates the inhibitory effect of laughter on the increase in PPBG and suggests the importance of daily opportunities for laughter in patients with diabetes. Nah, penelitian ini adalah salah satu dari sekian banyak penelitian yang mengungkapkan hal serupa, bahwa tertawa, senyum, berpikir positif dan bahagia mempunyai pengaruh langsung terhadap tubuh kita. Jadi sering-seringlah tertawa, namun tertawa yang ada sebabnya karena kalau tiba-tiba tertawa tanpa sebab itu malah kesannya horor seperti...
Apa yang kamu tertawakan, Nak?|| (c) here
Sumber : http://care.diabetesjournals.org/content/26/5/1651.extract

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